Effect of isolation on barbiturate anaesthesia in the rat
- 1 January 1976
- journal article
- research article
- Published by Springer Nature in Psychopharmacology
- Vol. 50 (1) , 85-88
- https://doi.org/10.1007/bf00634160
Abstract
The duration of barbiturate-induced sleeping in rats was found to be reduced by isolation housing. It was also lower in males than females, and lower in the dark phase of the diurnal cycle. These variables were shown to be additive in their effects. Sex differences in barbiturate action were found to be reduced by gonadectomy in males; and the effects of isolation were found to depend upon housing conditions at the time of testing rather than upon early rearing environment. The implication for theories of arousal is discussed.Keywords
This publication has 26 references indexed in Scilit:
- A critical period for social isolation in the ratDevelopmental Psychobiology, 1977
- Habituation of object contact in socially-reared and isolated rats (Rattus norvegicus)Animal Behaviour, 1976
- The development of intersession habituation and emergence in socially reared and isolated ratsDevelopmental Psychobiology, 1975
- Effects of neonatal androgens on open-field behavior and maze learning in the prepubescent and adult ratPhysiology & Behavior, 1975
- Mechanisms mediating the production of environmentally induced brain changes.Psychological Bulletin, 1975
- Mechanisms mediating the production of environmentally induced brain changes.Psychological Bulletin, 1975
- Effects of post-weaning environment on learning in the ratAnimal Behaviour, 1973
- Differential Activation by Restraint Stress of a Mechanism to conserve Brain Catecholamines and Serotonin in Mice differing in ExcitabilityNature, 1968
- Effect of prolonged individual caging on toxicity parameters in ratsFood and Cosmetics Toxicology, 1965
- Activity Rhythm in Peromyscus : Its Influence on Rates of Recovery from NembutalScience, 1963