Amino acid synthetic media for fungal pathogens based on aminopeptidase specificities:Histoplasma capsulatum, Blastomyces dermititidis, Paracoccidioides brasiliensis and Cryptococcus neoformans.

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Abstract
The development of simple and chemically defined liquid media for Histoplasma capsulatum, Blastomyces dermatitidis, Paracoccidioides brasiliensis and Cryptococcus neoformans according to their aminopeptidases profiles as amino acid requirement was described. When 1·5% purified agar was added, these media also supported excellent mycelial growth and sporulation of the deep mycoses. H. capsulatum was converted to and maintained in yeast phase when 0·1% L-cystine was added to the solid medium incubated at 37°C.