Enantioselective Total Synthesis of (+)-6-epi-Mevinolin and Its Analogs. Efficient Construction of the Hexahydronaphthalene Moiety by High Pressure-Promoted Intramolecular Diels−Alder Reaction of (R,2Z,8E,10E)-1-[(tert-Butyldimethylsilyl)oxy]-6-methyl-2,8,10-dodecatrien-4-one

This publication has 48 references indexed in Scilit:

• Inhibitors of cholesterol biosynthesis. 1. 3,5-Dihydroxy-7-(N-imidazolyl)-6-heptenoates and -heptanoates, a novel series of 3-hydroxy-3-methylglutarate-CoA reductase inhibitors
  Journal of Medicinal Chemistry, 1993
• HMG-CoA reductase inhibitors
  Natural Product Reports, 1993
• Total synthesis of dihydromevinolin and a series of related 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors
  The Journal of Organic Chemistry, 1992
• Synthetic studies on the mevinic acids using the chiron approach: total synthesis of (+)-dihydromevinolin
  The Journal of Organic Chemistry, 1990
• Total synthesis of both (+)-compactin and (+)-mevinolin. A general strategy based on the use of a special titanium reagent for dicarbonyl coupling
  Journal of the American Chemical Society, 1990
• Compactin (ML-236B) and related compounds as potential cholesterol-lowering agents that inhibit HMG-CoA reductase
  Journal of Medicinal Chemistry, 1985
• Microbial hydroxylation of ML-236B (compactin) and monacolin K (MB-530B)
  The Journal of Antibiotics, 1983
• Dihydrocompactin,a new potent inhibitor of 3-hydroxy-3-methylglutaryl coenzyme-A reductase from Penicillium citrinum.
  The Journal of Antibiotics, 1981
• Dihydromevinolin,a potent hypocholesterolemic metabolite produced by Aspergillus terreus.
  The Journal of Antibiotics, 1981
• Mevinolin: a highly potent competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase and a cholesterol-lowering agent.
  Proceedings of the National Academy of Sciences, 1980