Human gene for proliferating cell nuclear antigen has pseudogenes and localizes to chromosome 20
- 1 July 1989
- journal article
- research article
- Published by Springer Nature in Somatic Cell and Molecular Genetics
- Vol. 15 (4) , 297-307
- https://doi.org/10.1007/bf01534969
Abstract
We have isolated from a human genomic library a pseudogene of the proliferating cell nuclear antigen (PCNA)gene. Its sequence shows a 78% similarity with the human PCNA/cDNA. The PCNAgene is located on human chromosome 20, while the pseudogene maps to chromosome region Xpter→Xq13. An additional locus detected by the full-length PCNA cDNA, but not by intron probes, segregates concordantly with chromosome region 6p12→6pter and probably represents a second pseudogene.Keywords
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