Proteasome and transcription: a destroyer goes into construction
- 14 February 2006
- Vol. 28 (3) , 235-239
- https://doi.org/10.1002/bies.20379
Abstract
The proteasome is a proteolytic complex that is known to degrade proteins marked by the attachment of ubiquitin. Recently, it has become apparent that the proteasome has non-proteolytic roles. Several studies have implicated the proteasome in the regulation of transcription. A new study now shows that the proteasome facilitates the interaction of a histone acetyltransferase complex with transcriptional activators at active promoters. 1 Bioessays 28:235–239, 2006.Keywords
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