A zebrafish homologue of the murine Hox‐2.1 gene
- 28 March 1988
- journal article
- research article
- Published by Wiley in FEBS Letters
- Vol. 230 (1-2) , 25-30
- https://doi.org/10.1016/0014-5793(88)80634-3
Abstract
Homeobox-containing sequences were isolated from a genomic library of zebrafish (Brachydanio rerio). A λ clone containing two homeobox cross-hybridizing regions was characterized. DNA sequencing of one of these regions (ZF-21) revealed that it contains a homeobox closely related to the Antennapedia class of Drosophila homeobox sequences. Moreover, the deduced amino acid sequence of the C-terminal end (81 residues including the homeobox) is identical to the corresponding part of the murine Hox-2.1 protein. Similar to Hox-2.1, a ZF-21 derived transcript of 2.3 kb is present in embryos at the somite forming stages.Keywords
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