CROSS-NEUTRALIZATION OF OVINE AND BOVINE C-TYPE LEUKEMIA VIRUS-INDUCED SYNCYTIA FORMATION

  • 1 January 1977
    • journal article
    • research article
    • Vol. 37  (5) , 1486-1489
Abstract
Ovine leukemia virus (OLV) could not be distinguished from bovine leukemia virus (BLV) morphologically. Both C-type RNA tumor virus-producing cells induced syncytia when cocultivated with several indicator cells including [rat sarcoma] XC and [human glioma] KC cells. Syncytia formation could be blocked by antibodies against OLV and BLV, indicating that fusion was virus mediated. Antibodies against OLV and BLV exhibited reciprocal syncytial blocking properties, suggesting that OLV and BLV were closely related viruses.