The pitch of chromatin DNA is reflected in its nucleotide sequence.
Open Access
- 1 July 1980
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 77 (7) , 3816-3820
- https://doi.org/10.1073/pnas.77.7.3816
Abstract
A correlation analysis of chromatin DNA nucleotide sequences reveals the clear tendency of some of the dinucleotides to be repeated along the sequences with periods of 3 and about 10.5 bases. This latter period, which is equal within experimental error to recent estimates of the pitch of the DNA double helix [Wang, J. (1979) Proc. Natl. Acad. Sci. USA 76, 200-203; Trifonov, E. & Bettecken, T. (1979) Biochemistry 18, 454-456] is interpreted as a reflection of the deformational anisotropy of the DNA molecule that facilitates its smooth folding in chromatin.This publication has 55 references indexed in Scilit:
- The nucleotide sequence of bacteriophage φX174Published by Elsevier ,2004
- Coding potential and regulatory signals of the polyoma virus genomeNature, 1980
- The nucleotide sequence and genome organization of the polyoma early region: Extensive nucleotide and amino acid homology with SV40Cell, 1979
- Sequence of three introns in the chick ovalbumin geneNature, 1979
- Sequences of mouse immunoglobulin light chain genes before and after somatic changesCell, 1978
- The DNA sequence of sea urchin (S. purpuratus) H2A, H2B and H3 histone coding and spacer regionsCell, 1978
- The Genome of Simian Virus 40Science, 1978
- DNA folding in the nucleosomeJournal of Molecular Biology, 1977
- Mapping DNAase I-susceptible sites in nucleosomes labeled at the 5′ endsCell, 1976
- Folding of the DNA double helix in chromatin-like structures from simian virus 40.Proceedings of the National Academy of Sciences, 1975