Comparison of an enzyme-linked immunosorbent assay with indirect hemagglutination and hemagglutination inhibition for determination of rubella virus antibody: evaluation of immune status with commercial reagents in a clinical laboratory

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Abstract
Comparative evaluations of immune status [of humans] for rubella virus were described for enzyme-linked immunosorbent assay [ELISA], hemagglutination inhibition [HI], and indirect hemagglutination [IH]. A 92.1% agreement between ELISA and [IH] was demonstrated for rubella immune status. ELISA and HI demonstrated a 92.6% agreement and were compared in an attempt to define the quantitative usefulness of comparisons of single sera for determining immune status. Apparently, there is a relative lack of correlation between single ELISA and HI quantitative values. ELISA was an acceptable alternative to HI for the determination of immune status to rubella virus.