Tyrosine kinases in normal human blood cells
- 1 September 1986
- journal article
- Published by Wiley in FEBS Letters
- Vol. 205 (1) , 97-103
- https://doi.org/10.1016/0014-5793(86)80873-0
Abstract
The major tyrosine kinase from platelets was purified as a 51 kDa active enzyme which was shown to be a degradation product of the protooncogene product p60c-src. Immuno-depletion experiments using a monoclonal antibody recognizing p60c-src failed to remove band 3 phosphorylating activity from red blood cell membranes. The erythrocyte tyrosine kinase was not at all immunoprecipitated by this antibody under conditions where the platelet enzyme was immunoprecipitated.Keywords
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