Eosinophilia — Idiopathic or Not?

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Abstract
In countries where parasitic diseases are prevalent, these infections cause most cases of eosinophilia. Elsewhere, the majority of patients with eosinophilia are found to have atopy or, less often, drug hypersensitivity or a skin disease. There are numerous other causes of eosinophilia, but individually they are all rare.Eosinophilia may be primary or secondary. In patients with secondary eosinophilia, hematopoietic cells are normal and the increased production of eosinophils is a cytokine-driven reactive process. In patients with primary eosinophilia, there is an acquired abnormality of a hematopoietic stem cell. In some cases, differentiation is mainly to cells of the eosinophil . . .