Abstract
The permeability of blood capillary sprouts and newly formed blood capillaries, as compared to that of older blood capillaries, was studied by direct microscopic observation, using transparent moat chambers in rabbits'' ears. These studies show that in such chambers the blue dye T-1824, injected intravenously, passes more rapidly through the walls of blood capillary sprouts and newly formed blood capillaries than through the walls of older blood capillaries. Thus the permeability of blood capillary endothelium was found to vary with age, the more recently formed endothelium being more permeable.