A new synthesis of spirovetivanes via the spiro acyloin intermediate
- 1 July 1979
- journal article
- research article
- Published by Canadian Science Publishing in Canadian Journal of Chemistry
- Vol. 57 (13) , 1579-1584
- https://doi.org/10.1139/v79-256
Abstract
Ethyl-3-(1-ethoxycarbonyl-2,6-dimethylcyclohex-2-enyl)propionate 5 was stereoselectively synthesized. The diester 5 was spiroannulated by the acyloin condensation to give the bis(tri-methylsiloxy) ether 11. The ether 11 was hydrolyzed to provide the acyloins 6 and 12. The acyloins 6 and 12 were elaborated into (±)-hinesol 1, (±)-agarospirol 2, (±)-β-vetivone 3, and (±)-α-vetispirene 4.This publication has 5 references indexed in Scilit:
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