Substructure and whole molecule approaches for calculating log P
- 1 January 2001
- journal article
- Published by Springer Nature in Journal of Computer-Aided Molecular Design
- Vol. 15 (4) , 337-354
- https://doi.org/10.1023/a:1011107422318
Abstract
Lipophilicity is a major determinant of pharmacokinetic and pharmacodynamic properties of drug molecules. Correspondingly, there is great interest in medicinal chemistry in developing methods of...Keywords
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