Neutrophil-endothelial cell interactions on endothelial monolayers grown on micropore filters.
Open Access
- 1 February 1981
- journal article
- research article
- Published by American Society for Clinical Investigation in Journal of Clinical Investigation
- Vol. 67 (2) , 584-587
- https://doi.org/10.1172/jci110071
Abstract
We have developed a technique for growing endothelial monolayers on micropore filters. These monolayers demonstrate confluence by phase and electron microscopy and provide a functional barrier to passage of radiolabeled albumin. Neutrophils readily penetrate the monolayer in response to chemotaxin, whereas there is little movement in the absence of chemotaxin. This system offers unique advantages over available chemotaxis assays and may have wider applications in the study of endothelial function.This publication has 20 references indexed in Scilit:
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