Molecular Heterogeneity of the L-1 Metallo-β-Lactamase Family from Stenotrophomonas maltophilia
- 1 May 1998
- journal article
- research article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 42 (5) , 1245-1248
- https://doi.org/10.1128/aac.42.5.1245
Abstract
We have determined the nucleotide sequence of the blaS gene encoding the carbapenem-hydrolyzing L-1 β-lactamase from Stenotrophomonas maltophilia GN12873. Analysis of the DNA and deduced amino acid sequences identified a product of 290 amino acids. Comparisons of the L-1 amino acid sequence with those of other zinc β-lactamases showed 88.6% identity with the L-1 enzyme from S. maltophilia IID1275 and less than 20% identity with other class B metalloenzymes.This publication has 15 references indexed in Scilit:
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