Phytohemagglutinin-Induced Lymphocyte Transformation in Humans Receiving Δ 9 -Tetrahydrocannabinol
- 21 May 1976
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 192 (4241) , 805-807
- https://doi.org/10.1126/science.1265484
Abstract
Eight otherwise healthy male chronic marijuana smokers were hospitalized for a period of 30 days. Initially they received placebo, then a sustained dose of 210 milligrams of delta9-tetrahydrocannabinol (delta9-THC) per day for 18 days, followed by placebo. Lymphocyte responses to phytohemagglutinin were examined during each of these periods. Neither the daily ingestion of marijuana extract containing 210 milligrams of delta9-THC for 18 days nor the history of chronic marijuana smoking had a depressive effect on the lymphocyte responses of these subjects to phytohemagglutinin.This publication has 8 references indexed in Scilit:
- Antiemetic Effect of Delta-9-Tetrahydrocannabinol in Patients Receiving Cancer ChemotherapyNew England Journal of Medicine, 1975
- Mitogen-Induced Blastogenic Responses of Lymphocytes from Marihuana SmokersScience, 1975
- The PHA Dose-Response Curve: Validation of the Use of Logarithmic Graph Paper by Computer Analysis ResultsThe Journal of Immunology, 1974
- Normal Skin Test Responses in Chronic Marijuana UsersScience, 1974
- Impairment of Rosette-Forming T Lymphocytes in Chronic Marihuana SmokersNew England Journal of Medicine, 1974
- Inhibition of Cellular Mediated Immunity in Marihuana SmokersScience, 1974
- SHORT-TERM STORAGE OF HUMAN LYMPHOCYTES PRIOR TO IN VITRO STIMULATION1,2Transplantation, 1974
- Marihuana SmokingNew England Journal of Medicine, 1972