Effects of 2,4-Dichlorophenoxyacetic Acid on Chicks
- 29 October 1948
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 108 (2809) , 479-480
- https://doi.org/10.1126/science.108.2809.479
Abstract
The alkanolamine of 2,4-D was given orally to White Rock chicks. One part was diluted with 19 parts of water. The dose was given 3 times a wk. for 4 wks. The chicks were weighed before and after the expt. The differences between a control group and chicks given dosages of 0.28, 2.8, and 28 mg./kg. were not significant at the 5% level. The differences between controls and a group given a dosage of 280 mg./kg. were barely significant at the 5% level. Chicks all survived when given one dose of 380 mg./kg. All chicks died when given one dose of 765 mg./kg. On autopsy they showed fatty degeneration with a pale mottling of the liver, spleen, kidneys, and heart. There was hemorrhagic gastroenteritis. The results indicate that the alkanolamine of 2,4-D is not a cumulative poison since one dose of 765 mg. killed, but not a total dose of 3,360 mg. given over 4 wks.Keywords
This publication has 2 references indexed in Scilit:
- Effects of 2,4 - Dichlorophenoxyacetic Acid on Experimental Animals.Experimental Biology and Medicine, 1946
- Effects of 2,4-Dichlorophenoxyacetic Acid on the Ripening of Detached FruitBotanical Gazette, 1944