THE EFFECT OF INDORAMIN ON PERIPHERAL BLOOD FLOW
Open Access
- 1 February 1974
- journal article
- Published by Wiley in British Journal of Clinical Pharmacology
- Vol. 1 (1) , 13-17
- https://doi.org/10.1111/j.1365-2125.1974.tb00200.x
Abstract
The effect of indoramin, a new hypotensive agent, on peripheral blood flows of six normal subjects was determined and compared to placebo in a double‐blind, randomized study. Indoramin (0.25 mg/kg), administered intravenously, resulted in an increased forearm muscle volume as measured by strain gauge plethysmography and an increase in the skin temperature of the hand but not to the skin of the chest. It is concluded that these effects are the result of α‐adrenoceptor blockade.Keywords
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