COMPARISON OF 3 METHODS OF IMMUNIZATION AGAINST BOVINE ANAPLASMOSIS - AN EXAMINATION OF POST-VACCINAL EFFECTS

  • 1 January 1980
    • journal article
    • research article
    • Vol. 41  (7) , 1062-1065
Abstract
Normandy calves aged 7-11 mo. were immunized against bovine anaplasmosis, using a diluted virulent Anaplasma marginale stabilate of Colombian origin, diluted bovine blood containing an apparently mild strain of A. marginale isolated in Colombia or an attenuated A. marginale vaccine of ovine origin from the USA. Calves given the stabilate generally showed a moderate degree of parasitemia and reduction in packed cell volume (PCV). Calves given the apparently mild Colombian isolate of A. marginale developed moderate parasitemia, reduction in PCV and in some instances, required treatment to moderate the premunization procedure. Calves given the attenuated vaccine showed minimal evidence of parasitemia and PCV reduction. Most immunized calves became seropositive in the complement-fixation test for anaplasmosis and all calves sampled showed evidence of a cell-mediated response, using the leukocyte migration inhibition test.