Banding and spiralization of human metaphase chromosomes
- 1 January 1977
- journal article
- research article
- Published by Springer Nature in Human Genetics
- Vol. 36 (2) , 155-160
- https://doi.org/10.1007/bf00273253
Abstract
A new technique is described which produces spiralization of human metaphase chromosomes. The important feature is heat followed by trypsin treatment. By varying conditions, it is possible to produce bands, spirals and intermediate stages. This provides a new approach to the understanding of banding and chromosome structure.Keywords
This publication has 16 references indexed in Scilit:
- ELECTRON MICROGRAPHIC STUDIES OF THE EXPANDED AND UNCOILED CHROMOSOMES FROM HUMAN LEUKOCYTES*Annals of the New York Academy of Sciences, 2006
- Studies on the relationship of a collapsed chromosomal morphology to the production of Q- and G-bandsExperimental Cell Research, 1976
- Mechanisms of chromosome banding: II. Evidence that histones are not involvedExperimental Cell Research, 1974
- Correlation of the fluorescent banding pattern and ultrastructure of a human chromosomeExperimental Cell Research, 1974
- Staining Constitutive Heterochromatin and Giemsa Crossbands of Mammalian ChromosomesPublished by Elsevier ,1974
- Quantitative Constraints in the Arrangement of Human DNACold Spring Harbor Symposia on Quantitative Biology, 1974
- Mechanisms involved in the banding of chromosomes with quinacrine and Giemsa: I. The effects of fixation in methanol-acetic acidExperimental Cell Research, 1973
- Observations on human somatic chromosomes treated with hyaluronidaseCytogenetic and Genome Research, 1971
- The effect of two acetic acid containing fixatives on the histone content of calf thymus deoxyribonucleoprotein and calf thymus tissueExperimental Cell Research, 1968
- Demonstration of the Spiral Structure of Human ChromosomesNature, 1965