The effect of In(Lu) on some high‐frequency antigens
- 4 March 1986
- journal article
- research article
- Published by Wiley in Transfusion
- Vol. 26 (2) , 171-172
- https://doi.org/10.1046/j.1537-2995.1986.26286152909.x
Abstract
Antibodies to various high‐frequency antigens were used to test red cells of members of 12 families of Lu(a‐b‐) propositi carrying the In(Lu) gene. Kna, Kna‐like, McCa, and Sia usually are expressed more weakly on cells of the Lu(a‐b‐) members than on those of their relatives who were not Lu(a‐b‐). In most families, In(Lu) also suppresses Yka and Csa expression. Some antiserums are more efficient than others of the same specificity in demonstrating the weakened expression. The expression of Ch and Rg antigens on red cells is not affected by In(Lu).This publication has 7 references indexed in Scilit:
- The rare Lutheran blood group phenotype Lu(a–b–): a genetic studyAnnals of Human Genetics, 1984
- Human erythrocyte antigens. Regulation of expression of a novel erythrocyte surface antigen by the inhibitor Lutheran In(Lu) gene.Journal of Clinical Investigation, 1983
- Anti‐Wj: an autoantibody that defines a high‐incidence antigen modified by the In(Lu) geneTransfusion, 1983
- TWO MONOCLONAL ANTIBODIES DETECTING HIGH FREQUENCY ANTIGENS ABSENT FROM RED CELLS OF THE DOMINANT TYPE OF Lu (a‐b‐) Lu:‐3International Journal of Immunogenetics, 1982
- Observations on the Anton Antigen and AntibodyVox Sanguinis, 1982
- Antigens Aua, i and P1 of Cells of the Dominant Type of Lu(a–b–)Vox Sanguinis, 1974
- The Genetics of a Dominant Inhibitor of the Lutheran AntigensVox Sanguinis, 1973