Pretreatment of Urine Samples for the Analysis of 11-nor-Δ9-Tetrahydrocannabinol-9-Carboxylic Acid Using Solid-Phase Extraction
- 1 January 1990
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Analytical Toxicology
- Vol. 14 (1) , 39-44
- https://doi.org/10.1093/jat/14.1.39
Abstract
An extraction and concentration procedure using a unique solid-phase extraction tube was developed for the analysis of 11-nor-Δ9-tetrahydrocannabinol-9-carboxylic acid in urine. Absolute and relative recoveries of the drug metabolite were found to be greater than 85% and 92%, respectively. The extraction procedure allows quantitation of the drug metabolite by GC/MS, HPLC with UV detection, or GC with flame ionization detection. The extraction procedure was verified with urine samples obtained from marijuana users as well as spiked urine samples.This publication has 4 references indexed in Scilit:
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