Ten-Year Institutional Experience With Palliative Surgery for Hypoplastic Left Heart Syndrome
- 1 November 1995
- journal article
- research article
- Published by Wolters Kluwer Health in Circulation
- Vol. 92 (9) , 262-266
- https://doi.org/10.1161/01.cir.92.9.262
Abstract
Background We reviewed 212 consecutive patients who underwent stage I palliative surgery for hypoplastic left heart syndrome (HLHS) at our institution between January 1983 and June 1993. Methods and Results Six surgeons participated in the care of these patients. Follow-up is 97% complete. Preoperative anatomic and physiological factors and procedural features of the stage I operation were analyzed for impact on stage I mortality, survival to stage II palliation, and actuarial survival. Hospital mortality was not significantly lower during the second half of the study period (P=.242). Operative mortality was 46.2%. Multivariate analysis revealed improved stage I operative survival in patients with mitral stenosis (MS) and aortic stenosis (AS; P=.006). Additional risk factors for stage I mortality were a lower immediately pre–stage I pH (P=.034) and weight <3 kg (P=.015). Overall first-year actuarial survival for MS/AS was 59%, and it was 33% for all others (P=.001). Among stage I survivors, patients with ...Keywords
This publication has 14 references indexed in Scilit:
- Epidemiology of congenital heart disease in the United StatesAmerican Heart Journal, 1994
- Improving results with first-stage palliation for hypoplastic left heart syndromeThe Journal of Thoracic and Cardiovascular Surgery, 1994
- Cardiac Transplantation for Infants With Hypoplastic Left-Heart SyndromeJAMA, 1993
- A Comparison of the Perioperative Neurologic Effects of Hypothermic Circulatory Arrest versus Low-Flow Cardiopulmonary Bypass in Infant Heart SurgeryNew England Journal of Medicine, 1993
- Bless the babies: One hundred fifteen late survivors of heart transplantation during the first year of lifeThe Journal of Thoracic and Cardiovascular Surgery, 1993
- Intermediate procedures after first-stage norwood operation facilitate subsequent repairThe Annals of Thoracic Surgery, 1991
- Hypoplastic left heart syndromeThe Annals of Thoracic Surgery, 1991
- Hypoplastic left heart syndrome: more potential transplant recipients than suitable donorsThe Lancet, 1991
- Cardiac Allotransplantation in Newborns as Therapy for Hypoplastic Left Heart SyndromeNew England Journal of Medicine, 1986
- Physiologic Repair of Aortic Atresia–Hypoplastic Left Heart SyndromeNew England Journal of Medicine, 1983