Characterization of an unusual human histone H3.3 pseudogene
- 1 January 1991
- journal article
- research article
- Published by Taylor & Francis in DNA Sequence
- Vol. 2 (2) , 125-127
- https://doi.org/10.3109/10425179109039681
Abstract
The analysis of a genomic loci containing human histone H3.3 processed pseudogenes, has revealed two regions that are unusually rich in other retroposons. At one of the loci the H3.3 pseudogene is itself interrupted by 2 Alu repetitive sequences. The characterization of these two recently transposed Alus provides confirmation of the “multiple origin” hypothesis of these repetitive elements. The unusual occurrence of 3 different types of retroposons in a small region suggests that there may be particular chromosomal regions that are hot spots for retroposon insertion.Keywords
This publication has 9 references indexed in Scilit:
- Recently amplified Alu family members share a common parental Alu sequence.Molecular and Cellular Biology, 1988
- A fundamental division in the Alu family of repeated sequences.Proceedings of the National Academy of Sciences, 1988
- Sources and evolution of human Alu repeated sequences.Proceedings of the National Academy of Sciences, 1988
- Unusual structure, evolutionary conservation of non-coding sequences and numerous pseudogenes characterize the human H3.3 histone multigene familyNucleic Acids Research, 1987
- The multiple origins of human Alu sequencesJournal of Molecular Evolution, 1986
- Structure of a human histone cDNA: evidence that basally expressed histone genes have intervening sequences and encode polyadenylylated mRNAs.Proceedings of the National Academy of Sciences, 1985
- The Origin and Evolution of RetroposonsInternational Review of Cytology, 1985
- Nucleotide sequence definition of a major human repeated DNA, the Hind III 1.9 kb familyNucleic Acids Research, 1982
- DNA sequencing with chain-terminating inhibitorsProceedings of the National Academy of Sciences, 1977