Human maximization testing of D&C Yellow no. 10 and Yellow no. 11
- 1 September 1984
- journal article
- research article
- Published by Wiley in Contact Dermatitis
- Vol. 11 (4) , 210-213
- https://doi.org/10.1111/j.1600-0536.1984.tb00985.x
Abstract
By the maximization test, using 0.5% D&C Yellow no, 11 in pet, 15 of 20 human volunteers became contact sensitized. All reacted to a challenge concentration of 1000 ppm and one down to 1 ppm. The high allergenic potential of this dyestuff was confirmed. There were no cross reactions to purified samples of D&C Yellow no. 10. In contrail, 5% solutions of pure D&C Yellow no. 10 Tailed to sensitize human subjects. Cross reactions to this jubilance in persons sensitized to O&C Yellow no. 11 are due to impurities.Keywords
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