The Nuclear Segmentation of Eosinophils under Normal and Pathological Conditions

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Abstract
The nuclear segmentation of eosinophilic granulocytes was studied in leukocyte concentrates from normal subjects and patients with bronchial asthma, eosinophilia of other etiologies and ulcerative colitis. In the normal subjects the great majority of the eosinophlls contained 2 nuclear lobes, whereas the eosinophils from the patients presented a varying shift to the right A skin window'' experiment suggested that the ''shift to the right'' was caused by selective emigration of less segmented eosinophlls.