Methenamine-Silver Staining: a Simple and Sensitive Staining Method for Senile Plaques and Neurofibrillary Tangles
- 1 January 1994
- journal article
- research article
- Published by Taylor & Francis in Biotechnic & Histochemistry
- Vol. 69 (5) , 295-300
- https://doi.org/10.3109/10520299409106306
Abstract
An improved methenamine-silver impregnation method is presented which exhibits sensitivity for amyloid substances comparable to that of anti-beta protein immunostaining. In optimally treated sections, this technique stained both beta-amyloid deposits and neurofibrillary tangles, which are known to have a beta-pleated structure. This simple procedure allows a large number of sections to be stained for routine examination.Keywords
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