Retardation of ovarian growth in male-sterile mice carrying an autosomal translocation.

Publisher Website
Google Scholar
Abstract
Ovarian volumes in 3- and 5-day-old mice heterozygous for the t(11;19)42H translocation were found to be smaller than those of normal controls. Comparisons between littermates suggested a slight increase in body weight of the translocation bearers and this effect increased the difference in relative ovarian volumes between t42H/+ mice and controls. The differential effect of the translocation on fertility in males and females might be the result of the higher meiotic requirements inherent in spermatogenesis. [This study may be applicable to humans.].