Combinatorial biosynthesis for new drug discovery

This publication has 66 references indexed in Scilit:

• Analysis of eryBI, eryBIII and eryBVII from the erythromycin biosynthetic gene cluster in Saccharopolyspora erythraea
  Molecular Genetics and Genomics, 1998
• Engineering Broader Specificity into an Antibiotic-Producing Polyketide Synthase
  Science, 1998
• The Molecular Basis of Celmer's Rules: The Stereochemistry of the Condensation Step in Chain Extension on the Erythromycin Polyketide Synthase
  Biochemistry, 1997
• Biosynthesis of 2-Nor-6-deoxyerythronolide B by Rationally Designed Domain Substitution
  Journal of the American Chemical Society, 1997
• Ability of Streptomyces spp. aryl carrier proteins and coenzyme A analogs to serve as substrates in vitro for E. coli holo-ACP synthase
  Chemistry & Biology, 1997
• Biosynthetic short activation of the 2,3,6-trideoxysugar l-rhodinose
  Chemical Communications, 1997
• Production of a novel polyketide through the construction of a hybrid polyketide synthase
  Gene, 1996
• A hybrid modular polyketide synthase obtained by domain swapping
  Chemistry & Biology, 1996
• Molecular cloning of the whole biosynthetic pathway of a Streptomyces antibiotic and its expression in a heterologous host
  Nature, 1984
• Mutational Biosynthesis of New Antibiotics
  Annual Review of Microbiology, 1979