MODIFICATION OF ACTIVITY AND SURFACE-TOPOGRAPHY OF PERITONEAL MACROPHAGES BY CYTOPHILIC ANTIBODY
- 1 January 1978
- journal article
- research article
- Vol. 16 (1) , 37-+
Abstract
Scanning electron microscopy demonstrated that cytophilic antibody (Cab) attached to the [mouse] macrophage surface substantially changes the cell surface relief. Diffuse loss of surface structure was accompanied by diminished ability to interiorize opsonized sheep erythrocytes and to damage non-specifically bystanding target cells (chicken erythrocytes). Cross-linking of Cab on the macrophage surface by antigen or antibody partially restores macrophage membrane activity.This publication has 5 references indexed in Scilit:
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- CYTOPHILIC ANTIBODY IN GUINEA-PIGS WITH DELAYED-TYPE HYPERSENSITIVITY1964