Mars or Venus — Is Sex a Risk Factor for Recurrent Venous Thromboembolism?

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Abstract
In 1856 Rudolph Virchow identified three primary risk factors — commonly called Virchow's triad — for venous thromboembolism: venous stasis, hypercoagulability, and endothelial injury.1 Other risk factors have since been added to the list, and quantitative assessments now allow the classification of these factors as major (e.g., surgery) or minor (e.g., oral-contraceptive use).2 Although the patient's sex has not been implicated as an inherent risk factor for a first episode of venous thromboembolism, pregnancy and the use of estrogen-containing oral contraceptives are recognized sex-specific factors.The identification of risk factors is pivotal in the management of a first episode of . . .