Unresponsiveness to Hypoglycemia of Centers Controlling Epinephrine Release in Cerebral Infarct Patients

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Abstract
Urinary excretion of catecholamines under insulin hypoglycemia was studied in cerebral infarct patients and in patients with Parkinson''s disease and subjects with lumbar discopathy (control group). While in the last 2 categories of subjects a normal response to hypoglycemia, i.e., an increase in urinary excretion of epinephrine was noticed, no such increase was found in patients with cerebral infarction. The disorder is attributed to the unresponsiveness to hypoglycemia of the brain stem centers controlling epinephrine secretion.

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