A Convenient Synthesis of Aminomethylphosphonic Acid
- 1 June 1986
- journal article
- research article
- Published by Taylor & Francis in Synthetic Communications
- Vol. 16 (7) , 733-739
- https://doi.org/10.1080/00397918608059652
Abstract
A novel procedure for the preparation of aminometnylphosphonic acid (AMPA) is described. This compound. which has been shown to have some biological activity, is synthesized by treating N-hydroxymethylbenzamide with a mixture of phosphorous trichloride and trimethyl phosphite, followed by hydrolysis of the ester intermediate.Keywords
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