INFLUENCE OF FOOD ON THE ABSORPTION FROM DIFFERENT TYPES OF IRON TABLETS

1 June 1976

journal article
clinical trial
Published by Wiley in Scandinavian Journal of Haematology

Vol. 17 (S28) , 79-88
https://doi.org/10.1111/j.1600-0609.1976.tb00350.x

Abstract

The influence of a standardized breakfast meal on the absorption of iron from two types of iron tablets - rapidly-disintegrating and slow-release tablets - was studied in 24 healthy subjects, using a serum iron technique and whole-body counter measurements. The meal markedly reduced the absorption of iron from both types of tablets. An 8-fold reduction was found with the rapidly-disintegrating tablets and a 3-fold reduction with the slow-release tablets. Under fasting conditions the rapidly-disintegrating tablets were significantly better absorbed than the slow-release tablets, whereas the reverse was found when the tablets were given with the meal.

Keywords

IRON

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