Allergic contact dermatitis from 1,6‐diisocyanatohexane in an anti‐pill finish

Abstract
We report an outbreak of occupational allergic contact dermatitis from l,6‐diisocyanatohexane (old name hexamethylene diisocyanate or HDI), in the anti‐pill finish Evafanol AS‐1, in 2 clothing factories. The 19 Operatives Iron: 2 dressmaking mills all complained of work‐related dermatitis. 5 of the subjects had positive patch tests to the fabric with which they were working, and when all 19 were patch tested to Evafanol AS‐1 (1% aq). II were positive. 6 of these II were patch tested to MDI (l% pet.) and all 6 were positive. It appears that HDI in our group of clothing workers acted as a potent sensitizer affecting around 10% of the workforce.

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