Neurochemistry of GABAergic System in Cerebral Cortex Chronically Exposed to Bromide In Vivo
- 1 January 1987
- journal article
- research article
- Published by Wiley in Journal of Neurochemistry
- Vol. 48 (1) , 167-169
- https://doi.org/10.1111/j.1471-4159.1987.tb13142.x
Abstract
Neurochemical correlates of GABAergic synaptic transmission [binding, uptake, metabolism, and tissue content of .gamma.-aminobutyric acid (GABA)] were investigated in the cortex of rats that had been given 27 mM bromide in drinking water for periods of time ranging from 1 day 1 month. No effect of bromide on any of the parameters was found and it is concluded that chronic administration of bromide has no profound effect on GABAergic inhibitory system in the rat cortex.Keywords
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