Assignment of the gene locus for the sixth component (C6) of complement in mice to chromosome 15
- 1 December 1985
- journal article
- research article
- Published by Springer Nature in Immunogenetics
- Vol. 22 (6) , 637-642
- https://doi.org/10.1007/bf00430312
Abstract
A structural locus (C-6) for the sixth component of complement in mice is assigned to chromosome 15. Three-point linkage analysis indicated that the order of loci is C-6, Gpt-1, Gdc-1, and that the map distances are 25.9±4.9 between C-6 and Gpt-1, and 36.4±5.5 between C-6 and Gdc-1. Since Gdc-1 is more distal than Gpt-1, and C-6 is 26 cM away from Gpt-1, it is estimated that the C-6 is proximal to the centromere. In addition, a new C6 form found in AKR mice is described. We propose the designation C6B for it and C-6 b for the allele encoding C6B.This publication has 16 references indexed in Scilit:
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