An amphotericin B-resistant case of rhinocerebral mucor mycosis
- 1 May 1985
- journal article
- case report
- Published by Springer Nature in Infection
- Vol. 13 (3) , 134-136
- https://doi.org/10.1007/bf01642873
Abstract
Summary A 51-year-old male patient with diabetes mellitus complicated by ketoacidotic imbalance developed a rhinocerebral mucor mycosis that advanced despite early amphotericin B therapy and extensive surgical intervention. The MIC of amphotericin B for the isolated mucor species was 64 mg/l, meaning thatin vitro resistance also existed. Only long-term treatment with ketoconazole (600 mg/day, perorally) was successful in curing the disease.Keywords
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