New Chiral Stationary Phases with Two Chiral Centers for the Liquid Chromatographic Resolution of Racemic Anti-inflammatory Drugs Related to α-Arylpropionic Acids
- 1 June 1994
- journal article
- research article
- Published by Oxford University Press (OUP) in Chemistry Letters
- Vol. 23 (6) , 1021-1024
- https://doi.org/10.1246/cl.1994.1021
Abstract
New chiral stationary phases (CSPs) with two chiral centers were prepared from (R)- or (S)-α-naphthylethylamine and (S)-naproxen. The (R,S)-CSP prepared from (R)-α-naphthylethylamine and (S)-naproxen was found to be very successful in resolving 3,5-dinitroanilide derivatives of anti-inflammatory drugs related to α-arylpropionic acids.Keywords
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