Relationships Between Pulmonary Artery Pressure and Blood Flow in the Dog Lung

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Abstract
Measurements of blood flow and of inflow and outflow pressures were made in the left lower lobe of the lungs of 15 dogs. Pulmonary vascular resistance was calculated and found to vary inversely with inflow pressure and with flow. Typical pressure-flow and resistance-flow curves were presented. The form of these curves are unaffected by denervating the bronchus or by changing its ventilation, although resistance is increased by positive-pressure ventilation. The implications of the pressure-flow and resistance-flow relation-ships are discussed.