Exploratory laser flash photolysis study of free radical reactions and magnetic field effects in melatonin chemistry
- 1 November 1995
- journal article
- Published by Wiley in Journal of Pineal Research
- Vol. 19 (4) , 189-195
- https://doi.org/10.1111/j.1600-079x.1995.tb00188.x
Abstract
Melatonin is an excellent free radical scavenger, reacting with ferf-butoxyl and cumyloxyl radicals with rate constants of 3.4 × 107 and 6.7 × 107 M−1s−1, respectively. Reaction with benzophenone triplet occurs with a near-diffusion-controlled rate constant of 7.6 × 109 M−1s−1 in acetonitrile and probably involves charge transfer. When the radical pair formed by reaction of benzophenone triplet and melatonin is sequestered in a micelle, it is subject to extensive magnetic field effects that can be readily interpreted by the radical pair model.Keywords
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