Recurrent Venous Thrombosis and Portal Hypertension

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Abstract
THROMBOSIS occurring in both peripheral and visceral veins is well documented.1 2 3 4 Gerber and Mendlowitz3 could find no cause for the venous thrombosis in six patients, and they postulated a hypercoaguable state as the fundamental abnormality. In all these cases the thrombosis started in the extremities, and the viscera most commonly involved by venous thrombosis were the intestines, liver, brain, spleen, kidneys and adrenal glands.In the three patients with recurrent systemic venous thrombosis described below portal hypertension due to thrombosis of the portal vein subsequently developed. In one, the abnormal tendency to venous thrombosis was associated with a primary cryofibrinogenemia. . . .

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