Three-Dimensional Models of ACE and NEP Inhibitors and Their Use in the Design of Potent Dual ACE/NEP Inhibitors
- 1 January 1996
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of the American Chemical Society
- Vol. 118 (35) , 8231-8249
- https://doi.org/10.1021/ja950818y
Abstract
No abstract availableKeywords
This publication has 68 references indexed in Scilit:
- New Dual Inhibitors of Neutral Endopeptidase and Angiotensin-Converting Enzyme: Rational Design, Bioavailability, and Pharmacological Responses in Experimental HypertensionJournal of Medicinal Chemistry, 1994
- Heterocyclic lactam derivatives as dual angiotensin converting enzyme and neutral endopeptidase 24.11 inhibitorsJournal of Medicinal Chemistry, 1993
- Application of a conformationally restricted Phe-Leu dipeptide mimetic to the design of a combined inhibitor of angiotensin I-converting enzyme and neutral endopeptidase 24.11Journal of Medicinal Chemistry, 1993
- Angiotensin inhibition potentiates the renal responses to neutral endopeptidase inhibition in dogs with congestive heart failure.Journal of Clinical Investigation, 1991
- Mechanisms of atrial natriuretic factor-induced vasodilationPharmacology & Therapeutics, 1990
- Diverse biological actions of atrial natriuretic peptidePhysiological Reviews, 1990
- The Biochemical Pharmacology of Atrial PeptidesAnnual Review of Pharmacology and Toxicology, 1989
- Role of endopeptidase‐24.11 in the inactivation of atrial natriuretic peptideFEBS Letters, 1988
- Identification of protease 3.4.24.11 as the major atrial natriuretic factor degrading enzyme in the rat kidneyPeptides, 1988
- Dose-Dependent Effect of Atrial Natriuretic Peptide on Blood Pressure, Heart Rate, and Skin Blood Flow of Normal VolunteersJournal of Cardiovascular Pharmacology, 1986