Urothelial Proliferation In Growing Mice
- 1 March 1986
- journal article
- research article
- Published by Wiley in Cell Proliferation
- Vol. 19 (2) , 155-160
- https://doi.org/10.1111/j.1365-2184.1986.tb00725.x
Abstract
Developing murine urothelium undergoes pronounced proliferation until at least 10 days after birth. Thereafter, both mitotic and [3H]TdR-labelling indices fall sharply with age. The ratio of labelling to mitotic indices also alters dramatically during development, which is probably due to both endoreduplication and changes in the relative durations of the DNA synthesis and mitotic phases. This ratio reaches stability at 5 weeks of age. The adult labelling and mitotic indices were 0.11 and 0.019% respectively, indicating a very slow turnover.This publication has 13 references indexed in Scilit:
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