Activity of Tetracycline, Doxycycline, and Minocycline Against Methicillin-Susceptible and -Resistant Staphylococci
- 1 October 1974
- journal article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 6 (4) , 411-414
- https://doi.org/10.1128/aac.6.4.411
Abstract
Tetracycline, doxycycline, and minocycline were evaluated for their antibacterial activity against methicillin-susceptible and -resistant isolates of Staphylococcus . At clinically achievable levels both doxycycline and minocycline were more active than tetracycline against methicillin-susceptible organisms. Tetracycline and doxycycline had no activity against methicillin-resistant staphylococci, whereas minocycline at 2 μg/ml inhibited six of 13 strains and, at 3 μg/ml, 10 of 13 strains.Keywords
This publication has 15 references indexed in Scilit:
- Pharmacokinetic studies on minocycline in manClinical Pharmacology & Therapeutics, 1973
- Comparison of treatments with several antibiotics in experimental infections due to methicillin-resistant Staphylococcus aureus.1972
- The Slow Bactericidal Effect of Tetracycline and Minocycline on Wall-Defective StaphylococcusThe Journal of Infectious Diseases, 1972
- Bacteriological Evaluation of MinocyclineChemotherapy, 1972
- The mode of action of antibiotics on gram-negative bacilli.1971
- GROWING CLINICAL SIGNIFICANCE OF METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUSThe Lancet, 1968
- Methicillin-ResistantStaphylococcus aureusat Boston City HospitalNew England Journal of Medicine, 1968
- Absorption and Excretion of Five Tetracycline Analogues in Normal Young MenThe Lancet Healthy Longevity, 1968
- In Viho Activity of Minocycline, A New TetracyclineThe Lancet Healthy Longevity, 1968
- Susceptibility of Common Pathogenic Bacteria to Seven Tetracycline Antibiotics in VitroThe Lancet Healthy Longevity, 1968