MICROWAVE IRRADIATION IN ORGANOPHOSPHORUS CHEMISTRY 1: THE MICHAELIS-ARBUZOV REACTION

Abstract
A diverse series of phosphonate esters have been prepared using a domestic microwave oven. The microwave enhanced Michaelis-Arbuzov reaction shows remarkable rate acceleration under microwave irradiation and allows the facile synthesis, and in certain cases easy workup, of alkyl, α-substituted and aryl phosphonates.