Studies on Phenylpyruvic Oligophrenia. Phenylpyruvic Acid Content of Blood
- 1 December 1952
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 81 (3) , 715-720
- https://doi.org/10.3181/00379727-81-19998
Abstract
Phenylpyruvic acid was demonstrated in the blood of 39 patients affected with phenylpyruvic oligophrenia. The values ranged from 0.31 to 1.78 mg. per 100 ml. of plasma. A significant increase of phenylketonemia was observed following ingestion of DL-phenylalanine, the D-form causing considerably greater increase than the L-isomer. Feeding of phenylpyruvic acid resulted in a sharp increase of phenylketonemia. The significance of these findings is briefly discussed.Keywords
This publication has 4 references indexed in Scilit:
- Excretion of Phenylalanine and Derivatives in Phenylpyruvic OligophreniaExperimental Biology and Medicine, 1950
- Oligophrenia Phenylpyruvica II Constancy of the Metabolic ErrorExperimental Biology and Medicine, 1950
- STUDIES ON OLIGOPHRENIA PHENYLPYRUVICA .1. MICROBIOLOGICAL DETERMINATION OF L-PHENYLALANINE AND D-PHENYLALANINE AND OF PHENYLLACTIC ACID1949
- STUDIES ON PHENYLPYRUVIC OLIGOPHRENIA - THE POSITION OF THE METABOLIC ERROR1947