Radiotherapy for locally recurrent infantile pancreatic carcinoma (pancreatoblastoma)

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Abstract
The authors report a case of recurrent paacreatoblastoma in a 3-year-old girl who was successfully treated with radiotherapy. The patient had two local tumor recurrences before radiation treatment; the second recurrence was managed with radiation alone. Computerized tomography scan at the completion of radiotherapy showed dramatic tumor regression. Six weeks after radiotherapy was finished exploratory laparotomy was performed; multiple biopsies showed no evidence of tumor. The patient is currently disease-free 2 years after completion of radiotherapy. This case suggests a role for radiation therapy in the management of children with paacreatoblastoma.