Role of the RecF gene product in UV mutagenesis of lambda phage
- 1 July 1986
- journal article
- research article
- Published by Springer Nature in Molecular Genetics and Genomics
- Vol. 204 (1) , 82-84
- https://doi.org/10.1007/bf00330191
Abstract
E. coli recF mutants have a greatly reduced capacity for Weigle mutagenesis of ultraviolet light-irradiated lambda phage. A recF 332::Tn3 mutation was introduced into an E. coli recA441 lexA51 strain which constitutively expresses SOS functions. Weigle mutagenesis of phage lambda could occur in the resulting strain in the absence of host cell irradiation, and was increased when the recA441 (tif) allele was activated by increased temperature and excess adenine. The inability of recF strains to support Weigle mutagenesis can therefore be ascribed to a defect in expression of SOS functions after irradiation.This publication has 32 references indexed in Scilit:
- Non-targeted mutagenesis of unirradiated lambda phage in Escherichia coli host cells irradiated with ultraviolet lightJournal of Molecular Biology, 1984
- Changes in DNA base sequence induced by targeted mutagenesis of lambda phage by ultraviolet lightJournal of Molecular Biology, 1984
- Control of recA dependent activities in Escherichia coli: a possible role for the recF productMicrobiology, 1983
- Effects of a recA operator mutation on mutant phenotypes conferred by lexA and recF mutationsMutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 1982
- Mutagenesis resulting from depurination is an SOS processMutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 1982
- Influence of RecA protein on induced mutagenesisBiochimie, 1982
- recF-dependent recombination as a SOS functionBiochimie, 1982
- Genetic recombination of bacterial plasmid DNAJournal of Molecular Biology, 1982
- Mutagenic action of UV radiation on lambda prophageMutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 1980
- Genetic analysis of the recF pathway to genetic recombination in Escherichia coli k12: Isolation and characterization of mutantsJournal of Molecular Biology, 1973